Chronic Headache Infusion Therapy in Delaware

Woman enduring a chronic headache ices her head on a couch before scheduling IV therapy

Therapeutic Infusions offers Chronic Headache Infusion Therapy to our patients suffering from severe, debilitating headaches. We are committed to delivering exceptional care with a focus on personalized treatment strategies. Our team of skilled, personable healthcare professionals is lauded for our dedication to providing relief and improving the quality of life for our patients in a professional and compassionate setting. We are here to guide you through your journey towards better health.

 What is Chronic Headache Infusion Therapy?

 Chronic Headache Infusion Therapy involves the administration of medication through an intravenous (IV) line to treat chronic headaches, including migraines and cluster headaches. This therapy is typically considered when other treatments have failed to provide relief.

How does Infusion Therapy work for Chronic Headaches?

 Infusion Therapy for chronic headaches works by delivering medication directly into the bloodstream. This allows for faster absorption and can be more effective for some people than oral medications. Medications used can include anti-inflammatory drugs, steroids, magnesium, and drugs specifically targeting migraine mechanisms.

 What's in the Infusion?

At Therapeutic Infusions, our chronic headache infusion typically includes a combination of medications such as anti-inflammatory drugs, steroids, magnesium, and other specific migraine-targeting agents. The exact blend is tailored to each patient's needs and medical history.

Myers' Cocktail

A Myers' Cocktail is a nutrient infusion which includes a blend of vitamins and minerals. It's often used for a variety of conditions, including migraines. It contains ingredients like vitamin C, B vitamins, and magnesium, which can be beneficial for headache sufferers.

Occipital Nerve Blocks

Occipital nerve blocks are injections of a steroid and anesthetic around the occipital nerves located at the back of the head. They are used to treat headaches that are thought to be caused by irritation or inflammation of these nerves.

Trigger Point Injections

Trigger point injections involve injecting a small amount of anesthetic and steroid into areas of muscle in the neck and back. These are areas where knots, or trigger points, may contribute to headache pain.

The Benefits of Ketamine in Treating Acute Headaches

Therapeutic Infusions specializes in the targeted use of Ketamine, a medication known for its pain-relieving and anesthetic properties, has emerged as a promising option in the treatment of acute headaches, especially for individuals who have not found relief through traditional methods. Here’s why Ketamine can be an effective choice:

Rapid Pain Relief
One of the most significant advantages of Ketamine is its ability to provide quick relief from pain. Unlike some other treatments that may take time to become effective, Ketamine can offer relief often within hours of administration.

Effective for Resistant Headaches
Ketamine has been found to be particularly beneficial for those suffering from headaches that have not responded well to other treatments. This includes certain chronic migraines and cluster headaches, which are often resistant to conventional therapies.

Mechanism of Action
Ketamine works differently from traditional headache medications. It acts on the N-methyl-D-aspartate (NMDA) receptors in the brain. This action can help reset pain pathways, reducing the intensity and frequency of headache episodes.

Low-Dose Administration
In the treatment of headaches, Ketamine is used in much lower doses than when used for anesthesia. These lower doses minimize the risk of side effects while still providing effective pain relief.

Reduction in Associated Symptoms
Apart from alleviating headache pain, Ketamine can also help reduce related symptoms such as nausea, vomiting, and sensitivity to light and sound, providing a more comprehensive approach to symptom management.

Potential Long-Term Benefits
Some studies have suggested that Ketamine may have long-term benefits in headache management. Regular treatments might lead to a decrease in the frequency and severity of headache episodes over time.

Alternative for Those Who Cannot Take Traditional Medications
For patients who cannot take certain medications due to allergies, side effects, or contraindications, Ketamine offers an alternative that is often well-tolerated.


Comprehensive Headache Treatment Program:

This program is designed for patients with frequent headaches that significantly interfere with their life, functioning, or happiness or who have already tried multiple other treatments with minimal success. The program includes:

  • Six infusion days of ketamine and other headache medicines, including:
    • Dexamethasone
    • Toradol
    • Blocks of the Occipital Protuberance, Lesser and Greater Occipital Nerve,
    • Mastoid process, and Auriculotemporal nerve depending on symptoms
    • Ativan or Versed as needed
    • Optional NAD+                                                                                     +$100 per treatment
  • Maintenance infusions (if needed)
    • 1-hour infusion:                                                        $450 and includes cranial nerve blocks
    • 2-hour infusion:                                                        $650 and includes cranial nerve blocks
    • 4-hour infusion:                                                        $950 and includes cranial nerve blocks

Post-Traumatic Headache Treatment:

  • Includes all of the treatments above plus NAD+ brain restoration infusion therapy
  • Maintenance Infusions are $550 (includes NAD+)

Botulinum Toxin Treatment For Migraines:

Botulinum toxin has emerged as a promising treatment option for chronic migraines. While traditionally used for cosmetic purposes, its ability to relax muscles has shown effectiveness in reducing both the frequency and severity of migraine headaches. In clinical trials, onabotulinumtoxin A, a specific type of botulinum toxin, has been found to reduce migraine days by an average of 1.9 per month, offering significant relief to sufferers.

This therapeutic effect is thought to be related to the toxin's ability to block the release of pain-signaling chemicals, including calcitonin gene-related peptide (CGRP), which plays a crucial role in migraine development. By inhibiting this pathway, botulinum toxin can prevent the activation of pain pathways in the brain and nervous system, leading to fewer and less intense migraines. While further research is needed to fully understand the long-term implications of botulinum toxin for migraine treatment, its current effectiveness has established it as a valuable tool in the fight against this debilitating condition.

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Who is a good candidate for Chronic Headache Infusion Therapy?

This therapy is generally recommended for individuals who have not responded to standard oral medications or those who suffer from severe, debilitating headaches, including migraines. We conduct a thorough medical examination to determine if these therapies are appropriate for your condition.

Understanding Migraines

Migraines are a type of headache characterized by intense, often debilitating pain, typically affecting one side of the head. They are more than just a severe headache; migraines are a neurological condition and can have a significant impact on the quality of life of those who suffer from them. The characteristics and symptoms of migraines include:

  • Intense throbbing or pulsing pain
  • Duration of hours or days
  • Perceptual disturbances known as “Auras”
  • Nausea, Vomiting, extreme light sensitivity and/or sound sensitivity, dizziness, lightheadedness

Chronic Headache IV therapy targets key neural pathways believed to be responsible for migraines. Patients experiencing migraines have seen significant relief from these symptoms following infusion therapy. 

What to Expect

Side effects of Infusion Therapy

Like all medical treatments, Infusion Therapy can have side effects. These may include irritation at the injection site, allergic reactions to the medication, nausea, or dizziness. More severe side effects are rare but can occur, so constant monitoring during the infusion is essential.

How long does a typical Infusion Therapy session last?

A typical session can last from 30 minutes to several hours, depending on the medication used and the individual's response to the treatment. Some patients might require multiple sessions over several days.

How can I prepare for my first Infusion Therapy session?

Before your first session, it's important to eat a light meal and stay hydrated. Bring a list of your current medications and any allergy information. Wear comfortable clothing and consider bringing something to help you relax, like music or a book.

How Many Infusions Will I Receive?

The number of infusions depends on your individual response to the treatment. Some patients may see significant improvement after one session, while others might need multiple sessions. We will monitor your progress and adjust the treatment plan accordingly.

 After the Infusion

Post-therapy, some patients experience immediate relief, while others may notice a gradual decrease in headache frequency and intensity over time. Monitoring and follow-up with your healthcare provider are important to assess the effectiveness and make any necessary adjustments.

Available as a Standalone Treatment or Offered in Combination with Other Treatments

While infusion therapy can be effective as a standalone treatment, it is often more beneficial when combined with other treatments like oral medications, physical therapy, and lifestyle changes. Our healthcare team will work with you to determine the best comprehensive treatment plan.


The cost of infusion therapy can vary. We recommend discussing with your insurance provider for coverage details. We also provide a detailed cost breakdown before starting treatment for uninsured patients.


Private Rooms: We offer private infusion rooms to ensure comfort and privacy.

Medical Recliners: Our rooms are equipped with comfortable medical recliners.

Dimming Lights: We provide dimming lights in each room to ease light sensitivity.

Total Comfort:  We provide everything for your comfort during your treatment, including a pillow, blankets, eye masks, and noise cancelling headphones.

Monitoring by Trained Professionals: Our staff includes trained medical professionals who monitor patients throughout the infusion process.

What are the Risks of Chronic Headache Infusion Therapy?

While generally safe, risks include irritation at the injection site, allergic reactions, and, rarely, more severe side effects. We discuss all potential risks before starting treatment.

Safety Precautions

At Therapeutic Infusions, we ensure:

  • Comprehensive patient evaluation before treatment
  • Appropriate monitoring during infusion by trained professionals
  • Immediate response to any adverse effects
  • Follow-up care to assess and manage any long-term effects

Our priority is your safety and comfort, and we strive to provide the most effective and safe headache management possible.

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Safety first!

Full Crash Cart

We prioritize the safety and comfort of our Infusion patients, offering a full "crash-cart" on-site. This ensures immediate response to any medical needs, enhancing the treatment experience with an added layer of security and care.

Medical Grade Recliners

Our Chronic Headache IV Treatment patients can experience unparalleled comfort with our medical-grade recliners. These recliners are designed to provide optimal support and relaxation, ensuring a serene and comfortable environment during treatment sessions.

Medical doctor in house

Our Chronic Headache IV Treatments are administered with a fully trained and licensed medical doctor on-site. This guarantees immediate, expert medical attention in the rare event of an emergency, providing patients with an extra layer of security and peace of mind.

Private & secure

We understand that privacy during infusion treatments is very important that is why we offer treatments in a private room for all of our patients.


Changing lives and improving health


Jeanne-Marie Raziano, DMin, DDiv
Educated at Columbia, Penn and post-grad certifications from Harvard, Stanford & Rutgers.
Jeanne-Marie Raziano, DMin, DDiv
Jeanne-Marie Raziano, DMin, DDiv
Educated at Columbia, Penn and post-grad certifications from Harvard, Stanford & Rutgers. She has obtained her doctorate in ministry science as well as degrees in laboratory science, biology, and psychology. Jeanne-Marie has studied in molecular neuropharmacology, psychedelic therapy. She strives to bridge the gap between science and spirituality to help patients live healthier, more balanced lives. A life-long student of science, psychology, and spirituality to provide the best care possible. Jeanne-Marie is dedicated to creating a space of understanding and support for those dealing with crisis, trauma, and mental health issues. Offering counseling services and hosting support groups for LGBTQIA+ and survivors of childhood sexual abuse.
Joseph Raziano, MD
Medical Director
Dr. Raziano is a physician specializing in Emergency Medicine with an M.D. from Tulane University School of Medicine 
Joseph Raziano, MD
Joseph Raziano, MD
Dr. Raziano is a physician specializing in Emergency Medicine with an M.D. from Tulane University School of Medicine and a B.S. in Microbiology and Immunology from the University of Miami. He completed his residency at Emory University School of Medicine. Dr. Raziano is a board-certified and licensed physician in 8 states with more than 25 years of experience. He is helping people achieve their optimal health and well-being through cognitive and physical transformation. He is certified in Ketamine Therapy and IV Nutritional Therapy.

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Don’t wait, the start to a happier you starts today.

 Chronic Headache Infusion FAQ

Is Chronic Headache Infusion Therapy covered by insurance?
Coverage for Infusion Therapy can vary depending on the insurance provider and the specific plan. It is important to consult with your insurance company and the healthcare provider to understand the coverage details and any out-of-pocket costs.
Can I continue my regular headache medications during Infusion Therapy?
This depends on the specific medications you are taking. Some medications may need to be paused, while others can be continued. It's crucial to discuss this with your healthcare provider for personalized advice.
What are the Risks of Chronic Headache Infusion Therapy?
While generally safe, risks include irritation at the injection site, allergic reactions, and, rarely, more severe side effects. We discuss all potential risks before starting treatment.
Are there any lifestyle changes I should make during this treatment?
Lifestyle changes can complement Infusion Therapy. These might include maintaining a regular sleep schedule, managing stress, staying hydrated, and avoiding known headache triggers. Your healthcare provider can offer more tailored advice.
Do You Offer Counseling?
Yes, at Therapeutic Infusions, we offer counseling services as we understand chronic headaches can impact mental health. Our counselors specialize in pain management and coping strategies.
Do You Offer Vyepti?
Yes, we offer Vyepti, an intravenous medication specifically approved for the prevention of migraine. It's administered every three months and can be a part of your treatment plan.
Should I arrange a ride to and from chronic headache infusion therapy?
Yes, it’s a good idea to arrange a ride to and from your sessions. The medications used during the infusion can cause minor, transient side effects such as dizziness, fatigue, or mild disorientation, so driving yourself is not advised. Having a friend, family member, or a transportation service take you home ensures your safety and allows you to relax after the treatment. We can even walk you out to your Uber.
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