Wilmington, Delaware

Ketamine Infusion Therapy

Ketamine infusion therapy is a safe and legal treatment method that has been shown to treat anxiety, treatment-resistant depression, chronic pain, and PTSD. Therapeutic Infusions has trained medical professionals to administer treatment under close supervision.

Our Approach

What is Ketamine?

Ketamine is a medication that was first developed over 50 years ago for use as an anesthetic during surgical procedures. In recent years, however, the therapeutic potential of ketamine has expanded significantly, and it has been shown to be a highly effective treatment option for a range of mental health conditions, including major depression, bipolar depression, postpartum depression, anxiety, PTSD, OCD, as well as certain pain disorders such as fibromyalgia. This versatile medication has proven to be a valuable tool in the fight against these debilitating conditions, providing relief and improved quality of life for countless individuals.

Ketamine belongs to a class of medications called dissociative anesthetics, which work by blocking certain receptors in the brain and central nervous system. While it is still used for anesthesia today, the medication has garnered increasing attention in recent years for its ability to rapidly alleviate symptoms of treatment-resistant depression and other mental health disorders. In fact, ketamine has been found to be so effective that it is sometimes referred to as a "miracle drug" in the mental health community.

When administered in a controlled and supervised environment, ketamine infusion therapy has produced rapid and long-lasting relief of symptoms in individuals who have not responded to other forms of treatment. Unlike traditional antidepressant medications, which can take several weeks or months to take effect, ketamine works much more quickly, often producing noticeable improvements within hours of administration. In addition, research has shown that the effects of ketamine can last for several weeks or even months, allowing individuals to experience prolonged relief from their symptoms

  • Safe and effective
  • Legal
  • Treats PTSD, anxiety, treatment-resistant depression

Who is Ketamine Infusion Therapy for?


Ketamine infusion therapy has been found to be beneficial in treating depression due to its ability to rapidly increase the levels of neurotransmitters such as serotonin and glutamate which can help to reduce feelings of depression.


Ketamine infusion therapy can also be beneficial in treating anxiety due to its ability to reduce fear and anxiety responses in the brain, which can help to reduce feelings of anxiety and increase feelings of calm.


Ketamine infusion therapy has been found to be beneficial in treating PTSD due to its ability to reduce or even eliminate the intensity of traumatic memories, which can help to reduce the symptoms of PTSD and improve overall mental well-being.

Know someone who might benefit from ketamine services? Click here to book an appointment

Why Ketamine?


Ketamine Infusion Therapy has been proven to be very safe when administered properly, with very few side effects reported. It also has a low potential for abuse and addiction.


Studies have shown that Ketamine Infusion Therapy is an effective treatment for depression, anxiety, PTSD, and other mental health issues. It has also been used to treat chronic pain conditions.


Ketamine Infusion Therapy is legal when administered under the supervision of a trained medical professional.


The effects of Ketamine Infusion Therapy can be felt within minutes, making it a quick and effective treatment option.


Ketamine Infusion Therapy is a flexible treatment option as it can be administered in a variety of settings and tailored to the individual's needs. It is also a non-invasive treatment, making it suitable for a wide range of individuals.

Know someone who might benefit from ketamine services? Click here to book an appointment

About Your Appointment

How treatment is administered

Our clinic in Wilmington, Delaware administers ketamine infusion treatments at the office under close supervision. Here's how it works:

  • Start with a consultation to see if it's right for you.
  • Schedule your first session

The length of your treatment depends on the dose, but a session usually takes less than an hour. You must have someone to drive you home after your treatment.

To get the most benefits out of your ketamine infusion therapy, you will need a minimum of six infusions over two to three weeks. We will review the details of your treatment plan at your consultation so you know what to expect.

Frequently Asked Questions

Ketamine is legal for use under United States Federal law by registered medical practitioners, including settings such as ketamine clinics.

Ketamine has a broad range of "off-label" uses.  "Off-label" use is when a medication is prescribed by a licensed medical practitioner for any purpose other than the one specifically approved by the FDA.
It takes, on average, 10-15 minutes to feel the effects of the ketamine infusion.

Some of the most common experiences on ketamine include:
  • Heightened senses. You may feel more aware of instruments in the music you’re listening to, the softness of your blanket, or the intensity of different colors.
  • Deep relaxation or dissociation. Many patients describe feeling “floaty,” “light,” or like they are dreaming. The dissociation from ketamine infusion tends to be a pleasant or neutral experience, and it is believed that this state of mind allows for processing emotions without feeling overwhelmed.
  • Feeling happy or euphoric. It may make you feel happy or blissful. For patients suffering from depression, the euphoria from ketamine treatment can feel like a sudden relief from the daily weight of pain and worry.
We do take insurance, but only for Spravato.

While insurance does not cover IV Ketamine Therapy, we will provide you with a "superbill," an itemized invoice of the services rendered and proof of service.  Superbills are often used as part of out-of-network coverage, and in cases where the insurance provider would like more information around the submitted claim. You can speak to your insurance company regarding coverage.
Ketamine is commonly administered intravenously in the dose of 0.5 mg/kg.

Your dosage is not absolute. For some of our patients, we may actually start at a lower dose, because they may be sensitive to ketamine, such as in our patients that are older or younger. Your dose can also be increased if the doctor feels this is necessary.
In clinical trials, patients usually respond to it within one to three infusions. Many patients have reported relief within the first 24 hours.
Drugs like psilocybin, LSD, and DMT are known as "psychedelics" due to the quality of experience they invoke. These are grouped by their similar actions on the body’s serotonin receptors. Ketamine, while considered a psychedelic, is profoundly different. Its differences make it preferable as a treatment for various mental health disorders. Ketamine more consistently evokes a gentle "lifting" of existential burden. This is known as a "dissociative" effect and appears to free people from their anchors to their physical reality.
The physician will review your medical history and medication list to determine if there are any medications contraindicated with your ketamine infusion.
People with schizophrenia, or who have ever suffered a psychotic episode, should avoid ketamine. The drug has been demonstrated to bring back symptoms of psychosis, and these could persist beyond the period when the drug is in the body.
When people die after taking ketamine, they have usually combined it with another substance.

Taking with depressants (such as alcohol, GBL , benzodiazepines such as valium, or opiates such as heroin) may make you become unconscious quickly and unexpectedly, and can stop your breathing or allow you to suffocate on your own vomit.

Taking ketamine with stimulants (such as cocaine and ecstasy) may overload your heart. The chance of agitation and anxiety is also increased. Stimulants may keep you moving when the effects of ketamine would otherwise have immobilized you, increasing the chance of accidental injury.
Whilst many people use ketamine on occasion without feeling cravings, some people get addicted to ketamine use and may use it daily. People can struggle and fail to be able to stop using ketamine. Tolerance builds up, so users need much more ketamine to get the effects they like. Signs of tolerance should be considered an early warning sign of addiction and harmful use.

Book An Appointment

Don’t wait, the start to a happier you starts today. Our office is in Wilmington, Delaware.

Our Team

World Class Team

Jeanne-Marie Raziano, DMin, DDiv
Educated at Columbia, Penn and post-grad certifications from Harvard, Stanford & Rutgers.
Jeanne-Marie Raziano, DMin, DDiv
Jeanne-Marie Raziano, DMin, DDiv
Educated at Columbia, Penn and post-grad certifications from Harvard, Stanford & Rutgers. She has obtained her doctorate in ministry science as well as degrees in laboratory science, biology, and psychology. Jeanne-Marie has studied in molecular neuropharmacology, psychedelic therapy. She strives to bridge the gap between science and spirituality to help patients live healthier, more balanced lives. A life-long student of science, psychology, and spirituality to provide the best care possible. Jeanne-Marie is dedicated to creating a space of understanding and support for those dealing with crisis, trauma, and mental health issues. Offering counseling services and hosting support groups for LGBTQIA+ and survivors of childhood sexual abuse.
Joseph Raziano, MD
Medical Director
Dr. Raziano is a physician specializing in Emergency Medicine with an M.D. from Tulane University School of Medicine 
Joseph Raziano, MD
Joseph Raziano, MD
Dr. Raziano is a physician specializing in Emergency Medicine with an M.D. from Tulane University School of Medicine and a B.S. in Microbiology and Immunology from the University of Miami. He completed his residency at Emory University School of Medicine. Dr. Raziano is a board-certified and licensed physician in 8 states with more than 25 years of experience. He is helping people achieve their optimal health and well-being through cognitive and physical transformation. He is certified in Ketamine Therapy and IV Nutritional Therapy.
Kristen McGee, CRNP, PMHNP-BC
Nurse Practitioner
Kristen is a board certified psychiatric mental health nurse practitioner, having graduated from La Salle University with a Master of Science in Nursing.
Kristen McGee, CRNP, PMHNP-BC
Kristen McGee, CRNP, PMHNP-BC
Kristen is a board certified psychiatric mental health nurse practitioner, having graduated from La Salle University with a Master of Science in Nursing. Before entering the field of mental health, Kristen was a registered nurse working on a trauma unit. Spending time caring for trauma patients, and working closely with their families, inspired her to enter the field of mental health. Kristen worked as a psychiatric registered nurse while obtaining her degree. She cared for children and adolescents at an inpatient psychiatric facility. Kristen is also experienced in treating patients with substance use disorders, after completing clinical rotations at an inpatient rehabilitation center. Kristen has a holistic approach to patient care and provides compassionate, comprehensive mental health services to her patients.

Our Space

Here at Therapeutic Infusions we provide our clients with a safe, relaxed and private environment to feel comfortable working with us.

  • Private spaces
  • Shared spaces
Interior of a Therapeutic Infusions clinic room with a comfortable medical recliner chair, a side table with a medical monitor,  embodying the tranquility and professionalism of our ketamine therapy and vitamin infusion services

Safety first!

Full Crash Cart

We prioritize the safety and comfort of our Ketamine Infusion patients, offering a full "crash-cart" on-site. This ensures immediate response to any medical needs, enhancing the treatment experience with an added layer of security and care.

Medical Grade Recliners

Our patients can experience unparalleled comfort with our medical-grade recliners. These recliners are designed to provide optimal support and relaxation, ensuring a serene and comfortable environment during treatment sessions.

Medical doctor in house

Our Ketamine Infusion Treatments are administered with a fully trained and licensed medical doctor on-site. This guarantees immediate, expert medical attention in the rare event of an emergency, providing patients with an extra layer of security and peace of mind. All clinical staff is ACLS (Advanced Cardiac Life Support) certified.

Private & Secure Supervision

Every Ketamine Infusion treatment session is supervised throughout its entire duration, ensuring a secure and private experience. This approach is vital for maintaining comfort and enhancing the therapeutic efficacy of the treatment, providing patients with a safe, controlled environment for optimal care.