Therapeutic Infusions
Transforming Mental Health with Ketamine and FDA-Approved Spravato®
FDA-approved treatment, administered on-site in a REMS-certified medical setting with supervision and monitoring throughout each visit.
At Therapeutic Infusions, we specialize in innovative treatments that are transforming the way mental health conditions are addressed.
Our focus is on helping those who have not found relief through traditional therapies, providing hope for individuals suffering from treatment-resistant depression, PTSD. With expert care and the latest medical advancements, we offer both Ketamine Infusion Therapy and Spravato® (esketamine) to support our patients in their journey to improved well-being.
Therapeutic Infusions
- 1301 N Harrison St, Ste 102 Wilmington, DE 19806
- Call: 302-268-3353
- Fax: 785-414-5374
Two Convenient Locations
Wilmington’s Premier Ketamine Clinic and REMS-Certified Spravato® Treatment Center
Welcome to Therapeutic Infusions, your premier destination for advanced treatment of treatment-resistant depression and PTSD. As Delaware’s most trusted ketamine treatment center, we specialize in offering both Ketamine Infusion Therapy and Spravato® (esketamine)—two innovative, evidence-based treatments that provide fast and effective relief where traditional methods have failed.
Ketamine Infusion Therapy
Ketamine Infusion Therapy is a versatile treatment that can be used for a range of conditions, including treatment-resistant depression and PTSD. With its rapid onset of action, ketamine offers hope to those who haven’t responded to standard therapies, alleviating symptoms often within hours.
Depression
PTSD
Quick Action
FDA-Approved Spravato®
Spravato® is FDA-approved specifically for treatment-resistant depression. As a nasal spray enantiomer of ketamine, Spravato® offers a convenient and fast-acting solution for those who have tried other antidepressants without success. While related to ketamine, Spravato® is designed exclusively for depression and is administered in a safe, controlled clinical setting under medical supervision in a REMS-certified healthcare facility.
Treatment-Resistant Depression
FDA-Approved
Covered by Many Insurance Plans
Psychiatric Care
Talk Therapy and Medication Management, Now Available
Now accepting new patients with immediate availability
Getting a psychiatric appointment in Delaware often means waiting 3–6 months. At Therapeutic Infusions, our board-certified psychiatric nurse practitioners can see new patients right away — virtually or in-person.
This expanded service offers:
- Compassionate talk therapy and ongoing support
- Medication evaluation and management for depression, anxiety, ADHD, trauma, and more
- Flexible scheduling to fit your life
Whether you’re looking for dedicated psychiatric care or integrated support alongside your ketamine or Spravato® treatments, our team is here for you — without the wait.
Why Choose Therapeutic Infusions?
A Patient-Centered Approach
Providing care that is respectful of, and responsive to, individual patient preferences, needs and values, and ensuring that patient values guide all clinical decisions.
Evidence-Based Personal Care
We continuously apply and translate research findings in our daily patient care practices and clinical decision-making.
Private & Secure
We understand that privacy during infusion treatments is very important — that is why we offer treatments in a private room for all of our patients.
Evening & Weekend Hours Available
Flexible scheduling with evening and weekend availability. Appointments offered as late as 10pm, seven days a week. Phones answered Monday–Friday, 10am–6pm.
Comprehensive Support
From your initial consultation through ongoing care, we’re here to support you every step of the way.
REMS-Certified Spravato® Care
We meet all FDA requirements for administering Spravato®, including on-site treatment, medical supervision, and post-treatment observation.
Compassionate Care, Transformative Treatments
Ketamine Infusions
Experience the revolutionary treatment that has transformed the field of depression treatment. Providing fast action and profound shifts in perspective, studies have shown that Ketamine Infusion Therapy is an effective treatment for depression, anxiety, PTSD, and other mental health issues.
Spravato®
Spravato® (esketamine) is an isolated form of ketamine, and the only FDA-approved nasal spray for treatment-resistant depression. Spravato® offers rapid relief, often within hours, unlike conventional treatments that take weeks. Administered under professional supervision according to REMS protocols, this therapy is now covered by many insurance plans, reducing financial burden.
Ketamine-Assisted Psychotherapy
Ketamine-Assisted Psychotherapy combines the potent, rapid-acting antidepressant effects of ketamine with the deep, introspective insights of psychotherapy. This powerful combination can catalyze significant emotional and psychological healing, especially for those who have found traditional treatments to be insufficient.
Psychedelic Coaching
Our coaches provide personalized guidance to help you integrate the insights gained from your psychedelic journeys into your daily life. Whether you’re being treated with Ketamine, Spravato, or exploring other transformative practices, our coaching ensures that you translate those deep, introspective experiences into lasting personal growth.
Mental Health Consultation
Our expert team offers personalized mental health consultations to evaluate your needs and guide you towards the best treatment options. We’re here to help you find the right path to healing with care and compassion.
Psychiatric Therapy & Medication Management
Our psychiatric nurse practitioners provide talk therapy and medication management for depression, anxiety, ADHD, and more. Whether you’re new to treatment or looking for long-term support, we offer thoughtful, evidence-based care—no ketamine required. This is real mental health treatment, grounded in trust, expertise, and compassion.
Find Relief
When Traditional Therapies Fail
Learn how Ketamine and FDA-approved Spravato® target depression and PTSD at the source. Speak with a Wilmington clinician today.
We specialize in fast-acting treatments for complex mental health conditions. Contact us today to verify your insurance benefits.
Patient Reviews
Highly recommend. Superb treatment from staff. The (treatment) has made a huge difference for my daughter. After 2 weeks we saw a significant change, she is happier and able to do all the things she loves doing. One of the best things we have done for her.
Pete R., Wilmington
Therapeutic Infusions was and continues to be very instrumental in helping me achieve my optimal health and overall wellness. Joe and Jeanne Marie go above and beyond for each patient, treating us as the individuals we are, not the Medical Record Number assigned. Don’t waste another day living without hope – You don’t have to anymore!
Amanda K., Delaware
The staff treats you like you are part of their family and explains everything in depth. They are there with you through every step of the process and even walk you to your Uber/Lyft driver after the treatment. By far the best experience I have had dealing with my mental health!
Andrew E., Wilmington
Resources from Therapeutic Infusions
How Ketamine Differs from Psilocybin, MDMA, and Other Psychedelic Therapies
As interest in psychedelic-assisted therapy grows, many people are beginning to ask how different substances compare—and what role ketamine plays in this broader landscape. While psilocybin and MDMA remain in clinical trials, ketamine has quietly carved out its own space in modern mental health care, offering relief for those with conditions like treatment-resistant depression (TRD)…
Comparing Ketamine vs. Traditional Depression Treatments
For decades, depression has been treated with a combination of medications and psychotherapy, with varying degrees of success. While conventional antidepressants and talk therapy remain first-line treatments, they don’t work for everyone. Some individuals experience partial relief, intolerable side effects, or no meaningful improvement at all—especially those diagnosed with Treatment-Resistant Depression (TRD). Ketamine represents a…
How Long Do the Effects of Ketamine Last for Depression and PTSD?
Many people considering ketamine therapy for depression or PTSD wonder: How long do the benefits last? Unlike traditional antidepressants, which require daily use and take weeks to show effects, ketamine works rapidly—but its duration varies from person to person. How Quickly Does Ketamine Start Working? One of ketamine’s greatest advantages is its rapid onset of…