Spravato® Eligibility

Do I Qualify for Spravato® Treatment?

Spravato® is designed for adults with treatment-resistant depression who have not improved with traditional antidepressants. A consultation with our medical team can determine whether this treatment may be appropriate for you.

Understanding Eligibility for Spravato Therapy

Spravato® (esketamine) is an FDA-approved medication used to treat certain forms of severe depression. It is specifically designed for individuals whose depression has not improved with traditional antidepressant medications.

Many patients who consider Spravato have already spent years trying different treatments without relief. Determining eligibility involves reviewing your medical history, treatment history, and current symptoms.

At Therapeutic Infusions, eligibility is determined during a consultation with a medical provider experienced in treating treatment-resistant depression.

If you are still learning about the therapy, you can also read more about Spravato treatment in Delaware and how the medication works.

What Is Treatment-Resistant Depression?

The most common reason patients receive Spravato is treatment-resistant depression (TRD).

In general, depression is considered treatment-resistant when:

  • two or more antidepressant medications have been tried
  • medications were taken at appropriate doses
  • symptoms did not improve enough

Many people with treatment-resistant depression continue to experience symptoms such as:

  • persistent low mood
  • loss of motivation
  • difficulty concentrating
  • sleep problems
  • loss of interest in activities

Spravato works differently than traditional antidepressants and may help when other treatments have not worked.

How Many Antidepressants Must You Try Before Spravato?

In many cases, patients must have tried at least two antidepressant medications before Spravato is considered.

Your provider will review:

  • medication history
  • dosage levels
  • treatment duration
  • response to therapy

This review helps determine whether Spravato is an appropriate next step.

Insurance companies often require documentation of previous treatments before approving coverage. You can learn more about this process on our page explaining Spravato insurance coverage.

Who May Be a Candidate for Spravato?

Spravato may be appropriate for adults who:

  • have treatment-resistant depression
  • have tried multiple antidepressant medications
  • continue to experience significant depressive symptoms
  • are seeking alternative treatment options

Spravato is also approved for individuals experiencing major depressive disorder with suicidal thoughts or behavior.

A consultation helps determine whether the therapy is likely to benefit you.

Who May Not Be Eligible for Spravato?

While Spravato can be helpful for many patients, it is not appropriate for everyone.

Certain medical conditions or circumstances may require alternative treatment approaches.

Examples may include:

  • uncontrolled high blood pressure
  • certain vascular conditions
  • pregnancy
  • specific medication interactions

A physician will review your full medical history to determine whether Spravato is safe for you.

Because the medication can temporarily affect blood pressure and perception, treatment must take place in a medically monitored clinical setting.

You can learn more about the safety protocols used in our Spravato clinic with medical monitoring.

How Doctors Determine Eligibility

During a consultation, the clinical team reviews several factors to determine whether Spravato treatment is appropriate.

This evaluation typically includes:

  • review of depression history
  • prior medication treatments
  • medical history
  • current symptoms and severity

If Spravato appears appropriate, a treatment plan can be developed and insurance authorization may begin.

Book A Spravato Consultation

If you are wondering “Do I qualify for Spravato?”, the best way to find out is through a consultation with a qualified provider.

Our clinic provides physician-supervised Spravato treatment for patients throughout Delaware and surrounding areas.

Request a consultation today to learn whether Spravato treatment may be right for you.

Frequently Asked Questions

Spravato is typically prescribed for adults with treatment-resistant depression who have not improved after trying at least two antidepressant medications. A consultation is required to determine eligibility.
Treatment-resistant depression generally means that symptoms have not improved after trying two or more antidepressants at appropriate doses and durations.
Most patients have tried at least two antidepressants before being considered for Spravato. Your provider will review your treatment history during your evaluation.
Spravato is approved for depression, but your provider will evaluate your full medical and psychiatric history to determine whether it is appropriate for your situation.
Some medical conditions—such as uncontrolled high blood pressure or certain vascular issues—may make Spravato inappropriate. A physician will review your history to ensure treatment is safe.
In many cases, a referral is not required. Patients can schedule a consultation directly to determine eligibility.
Many insurance plans cover Spravato when patients meet eligibility criteria. Our clinic can help guide you through the authorization process.
If you qualify, the next steps include insurance authorization (if applicable) and scheduling your treatment sessions in a monitored clinical setting.
Our Team

World Class Team

Joseph Raziano, MD
Medical Director
Dr. Raziano is a physician specializing in Emergency Medicine with an M.D. from Tulane University School of Medicine 
Joseph Raziano, MD
Joseph Raziano, MD
Dr. Raziano is a physician specializing in Emergency Medicine with an M.D. from Tulane University School of Medicine and a B.S. in Microbiology and Immunology from the University of Miami. He completed his residency at Emory University School of Medicine. Dr. Raziano is a board-certified and licensed physician in 8 states with more than 25 years of experience. He is helping people achieve their optimal health and well-being through cognitive and physical transformation. He is certified in Ketamine Therapy and IV Nutritional Therapy.
Deddeh Yahntown, APRN, PMHNP-BC
Nurse Practitioner
Deddeh Yahntown is a board-certified psychiatric mental health nurse practitioner trained at Wilkes University 
Deddeh Yahntown, APRN, PMHNP-BC
Deddeh Yahntown, APRN, PMHNP-BC
Deddeh Yahntown is a board-certified psychiatric mental health nurse practitioner trained at Wilkes University, known for her commitment to providing compassionate, evidence-based care tailored to each patient’s needs. Her clinical background includes extensive experience in acute psychiatric care, mental health nursing, and substance use disorder rehabilitation, which has equipped her to handle complex patient challenges and foster recovery in demanding settings. With a deeply empathetic approach, Deddeh emphasizes trust-building and individualized care, integrating her academic foundation with real-world expertise to support holistic mental health. Her work is grounded in professionalism and compassion, making her a vital presence in the lives of those navigating psychiatric conditions.
Kristen McGee, CRNP, PMHNP-BC
Nurse Practitioner
Kristen is a board certified psychiatric mental health nurse practitioner, having graduated from La Salle University with a Master of Science in Nursing.
Kristen McGee, CRNP, PMHNP-BC
Kristen McGee, CRNP, PMHNP-BC
Kristen is a board certified psychiatric mental health nurse practitioner, having graduated from La Salle University with a Master of Science in Nursing. Before entering the field of mental health, Kristen was a registered nurse working on a trauma unit. Spending time caring for trauma patients, and working closely with their families, inspired her to enter the field of mental health. Kristen worked as a psychiatric registered nurse while obtaining her degree. She cared for children and adolescents at an inpatient psychiatric facility. Kristen is also experienced in treating patients with substance use disorders, after completing clinical rotations at an inpatient rehabilitation center. Kristen has a holistic approach to patient care and provides compassionate, comprehensive mental health services to her patients.
Stephanie Saw APRN PMHNP-BC
APRN PMHNP-BC
Stephanie is a board-certified psychiatric mental health nurse practitioner with a background in inpatient psychiatry, crisis care, and substance use treatment.
Stephanie Saw APRN PMHNP-BC
Stephanie Saw APRN PMHNP-BC
Stephanie is a board certified psychiatric mental health nurse practitioner (PMHNP) who earned her Bachelor of Science in Nursing from Wilmington University and her Master of Science in Nursing from Walden University. Before transitioning to her role as an advanced practice provider, Stephanie worked as a psychiatric nurse for years in a variety of settings, including inpatient and outpatient psychiatric facilities, crisis centers, substance abuse rehabilitation programs, and other healthcare facilities. As a PMHNP, Stephanie treats individuals across the lifespan, meeting people exactly where they are in their mental health journey. Stephanie believes every person has the capacity to live a balanced and fulfilling life. She creates a safe, supportive space for healing and personal growth.

Our Space

Here at Therapeutic Infusions we provide our clients with a safe, relaxed and private environment to feel comfortable working with us.

  • Private spaces
  • Shared spaces
Interior of a Therapeutic Infusions clinic room with a comfortable medical recliner chair, a side table with a medical monitor,  embodying the tranquility and professionalism of our ketamine therapy and vitamin infusion services